Best CBD Cream for Fibromyalgia

CBD based products have been popular for a while now. Everyone has heard of it. To summarize, CBD stands for cannabidiol which is a chemical extracted from the cannabis plant. Cannabidiol has shown to have several medicinal properties including anti-anxiety and pain relief etc. 

All these properties give CBD based products a useful underdog label. Fibromyalgia is a disease that causes both skeletal and muscular pain. The pain is usually widespread and affects joints, abdomen and even causes cognitive issues. 

Fibromyalgia cases are seen in adults mostly and can be quite bothersome. CBD creams have been known to work by affecting the nerve pathway that carries the signal for pain, this includes the case of fibromyalgia.

Our Overall #1 Rated Pick


Spruce CBD Topical Cream

  • Reliable and organic
  • Vegan-oriented
  • Third-party attested
  • No artificial sweetening

Fibromyalgia is a medical condition characterized by musculoskeletal pains. There can be many reasons like IBS, physical or mental trauma, even surgery that can cause these chronic pains. Regular supplements or medications are not much effective in granting relief so consumers look for an effective and natural remedy. 

The remedy is provided in the form of CBD topical cream by a well-reputed manufacturer. The company is renowned for its wide range of CBD-infused products. The secret to the efficacy of this product perhaps lies in its reliable and organic constituents.

Best CBD Creams for Fibromyalgia – Comparison Table




Best CBD Creams for Fibromyalgia – Product Reviews

Top 10 CBD Creams for Fibromyalgia out there

Spruce Topical CBD Cream

Fibromyalgia is a medical condition characterized by musculoskeletal pains. There can be many reasons like IBS, physical or mental trauma, even surgery that can cause these chronic pains. Regular supplements or medications are not much effective in granting relief so consumers look for an effective and natural remedy. 

The remedy is provided in the form of CBD topical cream by a well-reputed manufacturer. The company is renowned for its wide range of CBD-infused products. The secret to the efficacy of this product perhaps lies in its reliable and organic constituents. 

Fibromyalgia causes chronic pain that can be very cumbersome at times. The fast action of this cream guarantees a quick relief from the pains and unrest. The fast action is credited to the fusion of Cannabidiol and cannabis extract in the product. 

The company is known for its strict quality standards and protocols. All products are tested by local and third-party facilities to maintain their authenticity. Ingredients used are non-GMO and evaluated by the FDA. The tests ensure the absence of any harmful compounds or heavy metals.


  • Reliable and organic
  • Vegan-oriented
  • Third-party attested
  • No artificial sweetening 
  • No pesticides added


  • It is not completely free from THC. 0.3% content is present.

Spruce deep Chill CBD Lotion

As mentioned earlier, Spruce is famous for its wide range of products that cater to all types of consumers. One of the products from their topical range is the Deep Chills CBD Lotion. The use of reliable and vegan constituents makes sure the perfect formula is delivered to the consumers, ensuring maximum efficacy.

The product is mainly based on the fusion of cannabidiol and hemp extract. The extraction procedures adhere to the quality protocols and ensure the freshness and validity of the product. The CBD in the cream relaxes the receptor cells of the skin when applied, hence can be an effective aid against fibromyalgia pains. 

Additionally, the presence of aloe vera extract traps the moisture to ensure skin does not get dry. The cream also has an added methanol extract which initiates a cooling effect upon being applied to the skin. 

This effect helps the muscle to relax and can ease the fibromyalgia pains to a great extent. The product is tested and verified by independent and local facilities. It can be said the product is free from any harmful chemicals and is safe to use.


  • Attested by labs 
  • Aloe Vera to trap moisture
  • Menthol’s cooling effect
  • Rosemary essence
  • No artificial additives


  • It has traces of coconut oil; can be allergic to certain people. 
  • It is not 100% THC-free; might alert drug tests.

Spruce CBD Salve

Another entry from the Spruce product range is their CBD Salve. This ointment comes laced with organic, pure, and vegan ingredients which exhibit a fast action to relieve muscle stress and pain. Chronic pain is a major symptom of fibromyalgia, which can be effectively relieved using the CBD salve. 

The salve contains the perfect fusion of cannabidiol and hemp extract prepared by the teams of skilled professionals at Spruce. They make sure the best quality product is delivered to consumers that exhibit maximum efficacy. 

The cannabidiol acts on the CB-2 receptors in the muscles to help alleviate the feeling of pain throughout the body. Spruce’s CBD salves are completely reliable and safe to use. Evaluated by the FDA, and duly tested by independent and local labs alike, the product is free from any harmful chemicals.

Consumers must be aware of the slight THC content present, as it can cause issues if you’re going through a drug test.



  • Reliable
  • Non-GMO
  • Vegan-oriented 
  • Lab attested 
  • No heavy metals


  • 0.3% of THC present that can alert drug tests. 
  • Coconut oil in the salve can trigger allergic reactions in some people.

Cheef Botanicals CBD Salve

Cheef Botanicals CBD Salve

Founded by a group of hemp enthusiasts, Cheef Botanicals has over 25 years of experience in the food industry under its belt. Their teams of skilled professionals carry out extensive research to bring the best quality products for consumers that are on the lookout for effective and natural remedies. 

Their salves are loaded with the effective blend of hemp along with cannabidiol that acts on the CB-2 receptor cells of the skin to alleviate the sensation of any kind of pain. It boosts the human endocannabinoid system for swift action against chronic pains, as felt in the case of fibromyalgia.

The company has never compromised on the quality and adheres to the quality and safety protocols. All batches of the product are finalized only after due verifications from third-party testing. This eliminates any doubts or risks of chemical or heavy metal presence.


  • Third-party tested 
  • Economical 
  • Moisturizing action 
  • Antioxidants like vitamin E


  • None to be mentioned

Nature’s CBD Cream

Nature’s Labs is surely to be mentioned whenever someone talks about the best CBD companies in the market. The company has created a dedicated consumer base owing to its optimum quality products that deliver maximum efficacy. 

Their product range also contains CBD creams, which are the best answer for an organic remedy against chronic muscle pains and related issues. People experiencing pains related to fibromyalgia have benefited a lot from their CBD creams. 

Loaded with nothing but pure and vegan ingredients, the cream guarantees a swift action to alleviate all kinds of muscle pain. The company follows strict quality protocols and undertakes both local and third-party testing to authenticate the quality of their finished products. 

The testing ensures the products to be devoid of any harmful chemicals or heavy metals.



  • Organic additives 
  • Cannabinoid infused 
  • Effective 
  • Swift absorption 
  • Lab attested


  • Not for people allergic to menthol/camphor. 
  • Not to be used if undergoing a drug test.

Green Roads CBD Joint Cream

Green Roads CBD Joint Cream

Another company that deserves mention, as a well-reputed brand marketing CBD infused product range is Green Roads. It also sports a wide variety of CBD products to aid people who are looking for natural remedies to their problems.  

Fibromyalgia is a serious condition that often includes chronic muscle and bone pain. It can be caused by physical or mental trauma, and even as a side effect after surgery. People experiencing such an issue can find the best natural remedy in the form of Green Roads CBD cream. 

The cannabidiol and hemp extract in the product guarantee a swift action to alleviate all kinds of pains. The company has been in the CBD market for a long time and has garnered a lot of success owing to the efficacy of its products. 

The quality and validity are sure to be present, as each batch of products undergoes testing in local and third-party labs.



  • THC-free 
  • Vegan-oriented 
  • No Artificial sweetening
  • Scented 
  • Third-party attested


  • Expensive

Joy Organics CBD Cream

Joy Organics has been around long enough to etch their name as one of the top manufacturers of CBD-infused products. Their CBD creams are a must-have for people who are on the lookout for natural remedies to soothe their issues. 

Chronic pains are a major issue for people dealing with fibromyalgia and can prove cumbersome at times. People experience physical and mental traumas over time and can fall prey to this medical condition as a result. 

It can even be a post-surgery side effect for some.  The CBD cream utilizes its perfect blend of cannabidiol and hemp extract to alleviate the sensation of pain. It helps the muscles relax and lessens the pain. 

The products are safe and ready to use. Complete tests by third-party facilities validate the authenticity and safety of the products. Made with non-GMO ingredients, the products are evaluated by the FDA as well.


  • Safe to use
  • Third-party attested 
  • THC-free
  • Swift absorption 
  • Promotes skin health


  • Price is not economical. 
  • Contains essential oils, might prove allergic to some users.

Vertly Relief Lotion

Vertly is another name worth mentioning is the line of top competitors in the CBD product market. Owing to its quality standards and teams of skilled professionals, the brand delivers products that ensure swift and effective treatment from issues related to muscular or skeletal pains. 

Apart from its basic CBD-infused formula that helps in alleviating pain by acting on the receptor cells of the skin. The product also contains lavender oil which acts as an efficient anti-inflammatory agent. 

The presence of magnesium aids a lot in muscle recovery which makes it a key solution for fibromyalgia. The cream also has the addition of aloe vera and peppermint extracts which help keep the skin’s moisture intact after usage. 

It also boosts the condition of the skin. All products of Vertly are verified by third-party facilities and are deemed consumer-friendly.


  • Safe to use
  • Third-party attested 
  • Aids muscle recovery
  • Anti-inflammatory 
  • Promotes skin health


  • Can cause issues for people with naturally dry skin.

CBDistillery Cooling Cream

CBDistillery has ranked amongst the top manufacturers of CBD products. It has remained on top due to the introduction of new and improvised products in the market. Their team of researchers puts their best efforts to create the best CBD-infused product range for consumers. 

Their cooling cream is based on a premium fusion of hemp extract and cannabidiol. This mixture acts as a relief agent by acting upon the human endocannabinoid system. In addition to this basic function, the cream also has a “cooling” agent in rosemary extract. 

It creates a cooling effect that helps the muscles to relax and eases the pains. This cooling cream has proven beneficial for many people suffering from fibromyalgia and other chronic pain issues. 

CBDistillery has never compromised on quality. Adhering to all standards and strict safety protocols, the company makes sure the best products are delivered to consumers. Thorough testing of products is carried out before finalization.


  • Reliable
  • Broad-spectrum
  • Third-party verified 
  • Aids muscle relaxation
  • Promotes skin health


  • Contains 0.3% THC, might alert drug tests

Penguin CBD Cream

Penguin has climbed the ranks of top CBD product manufacturers in a very short time, owing to their quality products and exceptional customer service. Their research team has put a lot of effort into creating the premium blend of CBD-infused products for the market. 

A very economical option with a swift action rate, this cream guarantees relief from muscle pains and whatnot. People on the lookout for a natural remedy to their chronic pain issues should look no further than Penguin CBD Cream. 

Loaded with a fresh Peppermint-Lavender fragrance, the cream helps the muscles to relax and eases the sensation of pain. Penguin uses the best quality hemp grown in their farms in Oregon and adheres to all quality standards and safety protocols to ensure the delivery of a reliable product to their consumers.



  • Reliable
  • Scented
  • Third-party verified 
  • Helps muscle easing


  • Contains essential oils, might not fit well with some users.

Best CBD Creams for Fibromyalgia – Buying Guide

Properties of CBD

We are aware of the advantageous effects of CBD on receptors and the brain, but we are not sure about the molecular phenomenon between CBD and how the body responds to it. The University of San Paulo in Brazil investigated the working of CBD and concluded that CBD can activate a serotonin receptor, 5-HT1A. 

This receptor affects the biological processes and reduces the effects of anxiety, stress, and pain perception. This working mechanism votes in the favor of patients with fibromyalgia as it aids in relaxation and pain relief.

CBD interacts with some other ion channels and receptors. One of these channels is the TRPV1 or vanilloid receptor. What this receptor does is that generates pain, regulates body temperature, and even addresses inflammation. 

Interaction of TRPV1 with CBD can influence the pain perception in the patient. Both of these receptors play a vital role in pain perception and these receptors play a vital role in fibromyalgia patients. To ease the pain for physiotherapy, small-time use of CBD can prove to be quite flavorful. 

CBD will interfere with the pain receptors and allows you to carry out your exercise comfortably. We know that science has not been able to find a perfect cure for fibromyalgia but its symptoms can be treated. 

Constant medication and exercise are necessary for such patients. CBD can prove to be quite a vital addition to fibromyalgia patients.

Pain Relief

The most common use of CBD is in the domain of pain relief. People dealing with painful diseases often have to rely on some sort of pain reliever. Although nothing is more quick-acting than a prescribed pain relief medication, certain problems arise with being completely dependent on them. 

CBD being the plant-based product that it is, will have fewer side effects and other complications.  Long term use of CBD will be less harmful and even prove to be effective with time. CBD like most organic products is not rapid acting but its effects are long-lasting. 

Many research studies that endocannabinoid binding with the CBD can affect the sciatic nerve pain response and even affect the neurotransmitter interaction which will help bring down the sensation of pain and even inflammation.

Neuroprotective Properties

As we know now, CBD and its use in the treatment of several diseases and disorders are not very well known and the approach to it is rather hesitant. CBD has shown great potential to be a plausible treatment in some neuroprotective disorders such as epilepsy and ADHD.

Studies have shown that the use of CBD such as Sativex has shown positive results. The treatment and relaxation of muscle spasm. A few survey studies have shown that people with multiple sclerosis who used CBD sprays have shown pain relief and fewer spasms than those who didn’t.  

Children who suffer from Davet syndrome have also experienced fewer seizures due to the use of CBD. CBD is also useful in the treatment of seizures, convulsions, and spasms.  

Anxiety and Depression

Both anxiety and depression are mental disorders and require a proper medication course for proper treatment. The medication of both of these disorders causes several side effects such as drowsiness, fatigue, headache, etc. 

These side effects can cause many issues in everyday life. Along with that, these medications are also addictive. Abuse and misuse of these medications can lead to many problems. Several studies have shown that varying CBD doses for the treatment of both anxiety and depression show better results than placebos. 

In a survey study, a group of people suffering from these mental disorders was given a 30mg dose of CBD and another group was given a placebo 90 minutes before public speaking. People who took CBD showed fewer signs and symptoms of anxiety.

CBD and Fibromyalgia

As discussed earlier, fibromyalgia is not treatable as a whole. There is no cure for fibromyalgia but its symptoms can be treated for ease in day-to-day life. One of the most common symptoms of fibromyalgia is muscular and skeletal pain. 

This pain can range from bearable to extreme. Varying doses of CBD have shown that they can help ease the pain and help reduce the symptoms. A study done in 2016 has shown that pain stimulation and syndromes can also be due to a lack of endocannabinoids. 

These endocannabinoids bind to the cannabinoid receptors to create physiological processing including pain sensation. The lack of endocannabinoids can lead to headaches and even fibromyalgia. 

Doses of CBD can help to increase the number of endocannabinoids in the body which will encourage the proper physiological proceedings in the body and lessen the pain. This will create a lowered pain threshold among the patients with fibromyalgia. 

Usage and Dosage

The dosage of CBD is highly dependent on the disorder and the age of the person. For first-time users, CBD is usually advised to start with the smallest of doses. Although medicinal marijuana is prescribed for a wide variety of disorders, fibromyalgia is also cured using the cannabis plant.

While effective and approachable, the use of cannabis for any purpose is controversial. Hemp plants have this negative aura around them due to their notorious use for recreational purposes. Cannabis is used for medicinal purposes for a while and is a ton of research papers written regarding its wide range of properties.

 Due to the legality issues of cannabis, the showing of drugs in drug tests is not desirable. The use of a cannabis plant or any other hemp plant will lead to a positive result in a drug test due to the presence of THC. 

THC, also known as Tetrahydrocannabinol which is a psychoactive component of cannabis, is the compound responsible for the creation of a “high” effect. CBD creams or oils, on the other hand, have a minimum amount of THC in them, almost 0.3%. The amount this small won’t be able to show on a drug test and won’t create a “high” effect.


As of today, the usage of the cannabis plant for medicinal purposes is legal in only 33 states. This is due to the heavy misuse and abuse of cannabis for recreational purposes. This negative stigma around cannabis and the use of cannabis be it may for medicinal use, is very harmful. 

Although this view is changing a lot, the wider public still has a long way to go to understand the positive effects of all types of herb. Cannabis plant-based products are yet to be approved by the FDA but CBD has been declared safe to use the drug. 

Cannabis plants or hemp plants have a lot of other chemicals other than CBD which may or may not be safe. THC is labeled a schedule 1 drug which means that it is not known to have any medical effect or advantage. 

CBD drugs do not have a noticeable or harmful amount of THC in them making them safer to use in everyday life. This small amount of THC is not enough to create a high effect either.

Other benefits

Other symptoms of fibromyalgia include insomnia, headaches, cognitive disorders, and irritable bowel movement. As discussed above, CBD is known to have a positive effect on muscle pain and joint pain. CBD has also proven to aid in other symptoms as well. 

Insomnia can be treated with the help of CBD as it is a known relaxant. CBD helps to calm the nerve and reduce stress within the body. These properties will help to ease the person into sleep and sleep better. 

A recent survey study in 2019 showed that 66.7% of the selected individuals suffering from insomnia were able to sleep better and longer after just one month of CBD usage. Since CBD is not psychoactive, it won’t create a high sensation and would rather de-stress and relax you.

Full-spectrum CBD vs Isolate CBD

Full-spectrum CBD means that the product will contain not only cannabidiol but other chemicals as well such as CBC, CBG, and CNB. These additional phytochemicals will be non-psychoactive but with health benefits. 

As the name implies, full-spectrum means that it will have a wider range of phytochemicals in it all of which will work together. These full-spectrum CBD products have THC in them too. But, THC is present in such a trace amount that it won’t cause any psychoactive effect at all.

CBD isolates are a different story. Isolates mean that the product has only one type of chemical namely CBD. The pure form of CBD will work to heal and no other additive will be present. Even though the purity sounds nice, CBD will work relatively slowly as there will be no helping factors.

Now, is one of them better than the other, no. The full-spectrum will work faster, of course as all the phytochemicals will be able to create a synergic effect together.   

Best CBD Creams for Fibromyalgia – FAQs   

1. Which CBD form is best?

Full-spectrum CBD is usually advised to both new users and old. The entourage effect created due to the blend of all chemicals helps to heal quicker. Isolates are ideal for times when the patient is allergic to certain phytochemicals.

2. Is CBD legal?

The legality of CBD products is highly dependent on where you live. Some states have legalized it and some states haven’t. Due to it showing up in a drug test, a prescription to prove that the use is medicinal is mandatory. It is better to check if your state has made hemp or CBD legal or not. 

3. Is CBD safe?

CBD is safe to use both according to research and according to the experience of a lot of people. CBD is known to have medicinal properties which include muscle relaxant, anti-anxiety, sleep inducer, etc. CBD is completely safe and effective.

4. Is CBD effective? 

Yes, several research papers and survey studies have shown that CBD does interact with a few receptors that are responsible for pain stimulation and inflammation. An increase in endocannabinoids will show positive results by interacting with said neurotransmitters and easing both skeletal and muscular pain.  

5. Can CBD cure fibromyalgia?

Fibromyalgia, as of today, is not treatable. We can, however, reduce the symptoms. Muscular pain and joint pains are some of the most common symptoms and can be aided via CBD creams.  

Best CBD Creams for Fibromyalgia – Conclusion

Fibromyalgia affects 4 million people in the US alone and is usually found in young adults. With no absolute cure, Fibromyalgia is a struggle to live with. Reliance on pain killer pills is a must. Best CBD creams for fibromyalgia will help to reduce the local pain and will help you to limit or lessen your reliance on medications. 

CBD, being a natural product, can help fibromyalgia patients to find a balance and live a better life free of pain and stress.  

Here’s to a happier, healthier you!