Best CBD Oil for Depression

At one point or another, almost all of us have felt a bit under the weather. Sometimes our emotions become too loud to be controlled. And at moments feeling helpless in terms of feelings also puts us under the cloud. 

There is no set of definitive symptoms related to depression. It is different for every individual. The way it occurs, the reason for its occurrence, and the effects it has on our daily life are all different. But the solution to this problem is not very different as even though the mechanics and physical attributes of depression vary the chemical factors remain the same. 

The human brain has a very complex set of chemicals that regulate our mood and when a slight imbalance occurs problems like depression are generated. One solution that we have found to solve all of the problems regarding depression is CBD oil. 

There is much more insight and information present on the relation between CBD and mental health, give this article on which CBD Oil to buy for Depression a thorough read to understand their relationship better.

Our Overall #1 Rated Pick

Spruce 2400mg CBD Oil

  • 100% natural 
  • Vegetarian
  • Free from dairy ingredients 
  • Free from gluten

Spruce is listed as one of the well-known manufacturers of CBD oils. The 2400 mg CBD Oil is one of their products extracted from safe, organic, and vegan ingredients. Depression and anxiety are some of the common problems faced by teens and adults alike. 

Third-party and laboratory tests ensure that the oil is safe for use. A complete surety is attained about the oil is free from harmful heavy metals. The reports are kept transparent to the public to ensure that the company delivers quality as advertised.

Best CBD Oil for Depression – Comparison Table




Best CBD Oil for Depression – Product Reviews

Top 10 CBD Oil for Depression out there

Spruce 2400 mg CBD Oil

Spruce is listed as one of the well-known manufacturers of CBD oils. The 2400 mg CBD Oil is one of their products extracted from safe, organic, and vegan ingredients. Depression and anxiety are some of the common problems faced by teens and adults alike. 

Third-party and laboratory tests ensure that the oil is safe for use. A complete surety is attained about the oil is free from harmful heavy metals. The reports are kept transparent to the public to ensure that the company delivers quality as advertised. 

The fusion of hemp extract and CBD guarantees the best and quick results. The quick absorption of the oil helps speed up the process. Including immune system support, the oil also enhances neural activity in-turn improving sleep patterns.

The oil includes dairy-free, gluten-free, and non-GMO ingredients. No artificial sweeteners, preservatives, pesticides, or additives are involved in making the oil. It ensures 100% safety for consumption.


  • 100% natural 
  • Vegetarian
  • Free from dairy ingredients 
  • Free from gluten 
  • Non-GMO 
  • No additives
  • No preservatives added 
  • Properly laboratory-tested


  • Contains THC; which might get picked up in drug tests.

Spruce 750mg Lab-grade CBD Oil

People experience depression, as well as daily stress. It is a serious problem that ideally needs to be addressed. Depression is without question one of the most tragic and recurrent psychological disorders of today. This also turns your social and personal life upside down.

It is an intricate disorder, and no proper treatments exist. Spruce is the ultimate best choice regarding the best laboratory CBD oil for depression. It is laced with organic ingredients. No chemical preservatives, sweeteners, or flavors are present in the oil. 

It has an aroma of peppermint which makes it very easy to consume. What’s more, most people now prefer to eat vegetarian diets, and this oil will suit them to a great extent. 

It is vegan and gluten-free oil. It contains 100% natural hemp seed oil, natural flavors and is free from pesticides.


  • 100% natural 
  • Full Spectrum 
  • Vegetarian
  • Free from gluten
  • No artificial aroma added 
  • No preservatives added 
  • Laboratory-graded 
  • Third-Party tested and graded


  • Cannot be used if you are to undergo any drug testing. 
  • Includes less than 0.3% THC.

Spruce 4800mg Extra Strength CBD Oil

Spruce’s 4800 mg oil is a famous laboratory-graded product. It resembles all the other CBD Oils but does include a difference which is its extra-power. People having stress, depression or anxiety-related problems have to resort to high potency medications. Whereas, it is better to have a natural treatment. 

It boasts Full Spectrum hemp which is obtained from natural sources. CO2 extraction is utilized to obtain the hemp whilst maintaining the legibility of the product. Laboratory and third-party tests add further to the validity of the product. 

What’s more, even though it is a full spectrum of CBD oil, no type of intoxication is caused by the usage of this oil. This CBD oil exhibits a comparatively higher potency than the other oils, the THC content stays unchanged at 0.3% so it does not initiate the hyper-active condition. 

However, users need to be careful as even minor amounts of THC can pop up on drug tests.


  • Pure 
  • Vegetarian  
  • Non-GMO 
  • Gluten-free
  • Full Spectrum 
  • No stabilizers 
  • No artificial flavor enhancers 
  • Laboratory-graded


  • Contains minor traces amount of THC
  • Should be avoided if you are subject to any drug test

Spruce 400mg Extra Strength (Sample Size)

This Spruce CBD Oil is meant to facilitate the first-time users, who are usually reluctant to purchase a bigger bottle. It has abaca oil extract. The quality of abaca is not compromised because of the use of CO2 extraction. 

The oil is Full Spectrum. All of the ingredients are unprocessed, vegetarian, and checked. Oil undergoes tests in local laboratories as well as an intermediate laboratory. Testing verifies the absence of harmful metals and compounds. 

It comes with a dropper that measures the exact dosage for the user. Consultation with a physician is always advised before the usage of such products. The oil is highly graded and has no added enhancers or stabilizers. The product has to be stored in places not having moisture and heat.


  • Unprocessed  
  • Vegetarian 
  • Improves neural function
  • Protects from disorders  
  • Increased potency 
  • Free from gluten  
  • Laboratory verified 
  • Mediator verified


  • Sample-size means less content in the bottle. 
  • Includes minor traces of THC that can alert drug tests.

Cheef Botanicals CBD Oil

Some health experts grouped and introduced Cheef Botanicals. It markets products having crude and unrefined ingredients. People battling with complex disorders found using the oil very helpful. The oil is known to drastically reduce and ease pains, anxiety, and most of all depression. 

The abaca essence contained in the product is obtained following carbon-dioxide distillation. It ensures quality remains uncompromised. The product is also verified in both local and intermediate laboratories to verify the absence of heavy metals and harmful compounds. 

The company has never risked anything over quality. That’s the reason they deliver everything that is advertised. Oil is the perfect natural remedy for such complex problems. It is laced with fatty acids that act on both the neural functions and improve immunity. Regular usage of the product guarantees healthy living. 

Any type of additional stabilizers, flavor-enhancers, or chemicals are completely absent in the oil. Although some other supplements might not fit well with some users.  It is advised to consult with doctors before using the oil.


  • 100% natural
  • Vegetarian 
  • Laboratory verified
  • No THC present
  • No added enhancers  
  • No stabilizers 
  • Non-GMO  
  • Free from gluten


  • None

Green Roads CBD Oil

The list of well-known CBD Oil manufacturers would be incomplete without the mention of Green Roads. Their oils are formulated by trained pharmacists featuring a premium mixture of cannabis-derived essence. 

It’s manufactured with a wide variety of beneficial compounds in cannabis plants, and includes only 0.3% THC, legally abiding by the federal limit. People battling with anxiety, stress, depression, and other such cognitive problems have stated to find usage of the oil very beneficial in their recovery. 

The oil is based on the native cannabis essence and includes all important vitamins while also leaving out unnecessary compounds that can give mixed reactions. It has everything in it to guarantee a calm and pleasant mind free from depression.

There exist many sources for the intake of CBD, like vape pens, gummies, and whatnot.  But oil is said to be the best owing to its swift action and quick absorption. The oil is verified in a local laboratory as well as by an independent laboratory to make it best in quality. 


  • Soy-free
  • No gluten 
  • With natural flavor
  • Laboratory verified 
  • Unique flavors 
  • Variety of potencies 
  • No enhancers or additives
  • Non-intoxicating


  • Expensive

CBDistillery CBD Oil

Founded not long ago, CBDistillery has made its way into the list of major companies of CBD Oil. CBDistillery is known best for its native, economical, and efficiency. THCs, enhancers, and additives are absent from the oils. 

The ingredients are unprocessed and free from harmful compounds. The company verifies its products through an independent laboratory to guarantee that the quality of the product is proper, as advertised. CBDistillery is included in the list of companies that boast a U.S. Hemp certified legal permission. 

It ensures a high standard of oil. The very economical range of prices for the full spectrum and THC-free CBD Oil range is a very pleasing plus point. Absorbing the oil under your tongue would ensure proper fast action and good results. 

This way, the oil directly enters the bloodstream. It provides amazing results in balancing stress levels, relieving anxiety, and relieving depression by bettering the sleep patterns.


  • Natural
  • Full-spectrum 
  • Independent lab verification 
  • Proper U.S. Hemp Authority Permit 
  • No preservatives


  • Not a wide flavor range present  
  • Not tested for the presence of any heavy metals.

Royal CBD Oil

Royal CBD Oil is part of the top-notch CBD Oil companies. The oil includes native and healthy ingredients. The product is furthermore available in a wide variety of potencies. For people relying on supplements and medications to battle stress and depression, CBD Oil is the ultimate remedy. 

It comes with a dropper included with the package to measure the accurate dosage. The oil contains other important vitamins and nutrients. Dosage can be increased or decreased accordingly. The key to a proper remedy is a consistent dosage. 

It has plant-based, and soy-free ingredients. The abaca is obtained from organic sources. It is easily consumable. The oil has an economic price range, also considering its high-quality. 

If placed under the tongue and held for a mere ninety seconds. It gets absorbed into the bloodstream directly. That makes it a fast-action and quick absorption oil. The best part about the oil is it boosts immunity and has a positive effect on cognitive activity.


  • Enhances neural functioning 
  • Vegetarian  
  • Range of potencies 
  • Free from additives  
  • Laboratory verification 
  • Independent verification


  • Not evaluated by FDA 
  • Not free from THCs

Lazarus Naturals CBD Oil

The Lazarus Naturals ranks amongst the major manufacturers of CBD Oil. It has shown its efficiency in benefiting people with stress-related problems and depression. Consistent usage of the oil in proper doses shows visible results. 

The cannabis essence is obtained from the domestic farms of cannabis using organic procedures. The oil’s packaging includes a dropper to help measure the dosage with accuracy. The best part about oil is its fast-acting nature and quick rate of absorption. 

The oil once placed under the tongue gets absorbed into the bloodstream directly. The ingredients are native and free from any type of dairy additives or gluten. No traces of enhancers, preservatives, or stabilizers in the product. 

The oil, however, includes minute amounts of coconut oil and organic flavors. The chocolate mint flavor is one of the most-consumed. The ethanol procedure is followed for extracting oil that maintains purity and safety.


  • Organic 
  • Non-GMO 
  • Improves brain functioning 
  • Lab-Tested 
  • Releases anxiety


  • Coconut oil can have allergic reactions to some people.
  • Oil has not undergone evaluation from the FDA

Joy Organics CBD Oil

The Joy Organics CBD Oil is enlisted as one of the premium-grade CBD oil manufacturers. People who are battling imbalanced stress levels and depression find it beneficial. The secret to proper remedy is being consistent. Oil can be consumed with or without food depending on the user’s discretion. 

Being THC free is the best part about this oil. Hyperactivity and problems related to it can damage your life. Constant usage of THC products might play a part in such issues. The abaca is extracted from the natural source-farm using the process of carbon-dioxide extraction. It helps to keep the safety and purity of the product intact, just as the company advertises.

The oil exhibits a swift action and quick rate of absorption. Placing it under the tongue, it directly gets absorbed right into the bloodstream. Verifications both by local and independent laboratories make sure no question arises about the quality of the product. There are zero traces of hazardous compounds and metals in the oil. 

The oil has native, organic, and non-GMO ingredients. Storage should be considered in a cool place away from humidity and moisture. In this way, the purity and efficiency of the product are kept intact.


  • Organic 
  • Vegetarian
  • Lab-verified 
  • Free from THC
  • Quick Action 
  • A high rate of absorption


  • Expensive

Best CBD Oil for Depression – Buying Guide

To be able to choose the right type of CBD oil is vital to the treatment of depression and we are here to help you choose the best for yourself and your loved ones. There are many variations of CBD oil present in the market and each variation is based on different concentrations of cannabinoid elements. 

If you understand the basic mechanisms that are involved in the production of CBD oil you will surely be able to understand the basic differences between the variants of CBD oil. Here we have compiled a detailed explanation of all the things that you must understand to choose the best CBD oil for depression. 

The Spectrum of CBD Oil

There are three main spectrums of CBD oils that you will often encounter. The Full-spectrum, broad-spectrum, and CBD isolate. These three spectrums vary in terms of the composition of the cannabinoid elements present in the CBD oil. 

Apart from CBD, there are 113 elements in the cannabinoid family only one of which is responsible for intoxicating effects associated with marijuana. The broad-spectrum CBD oil contains all the elements of the cannabinoid family apart from THC. 

Therefore, this option is chosen by people that are subjected to drug tests often and cannot risk a false positive due to minute amounts of THC present in their therapeutic oil. The full-spectrum CBD oil provides all the benefits of the cannabinoid family including the benefits associated with THC minus the intoxicating effect. 

The concentration of THC in this spectrum is limited to minute amounts hence cannot produce the ‘high’ state associated with marijuana. The last but not the least option is the CBD isolate, and as the name suggests this spectrum of CBD oil only features cannabidiol and no other elements. 

It is said to be the least effective of all three options but still good enough to produce a moderate response. The choice of the spectrum of CBD oil is all yours as there aren’t any significant pros and cons associated with them apart from the presence or absence of THC for you to question its integrity. 

The functionality of all three spectrums is quite similar with a small difference of entourage effect produced by full-spectrum and broad-spectrum CBD oils. 

THC Percentage 

THC is the most controversial element involved in the production and manufacturing processes of CBD oils. THC is tetrahydrocannabinol and it is the only psychoactive intoxicating element from the vast family of cannabinoids. 

The reason there was an extensive ban on the production and consumption of CBD products was because of the misconception that CBD might also produce an intoxicating effect like THC. But latest research has conclusively proved that while THC and CBD do share some properties the ability to produce a ‘high’ state is only limited to the properties of THC. 

There is even a safe level of THC that can be consumed regularly without having to bear through the intoxication. After careful deliberation and countless research studies, the FDA has set the level of THC safe for consumption and minute amount of equal to or less than 0.3 percent. 

This percentage of THC is also the basis of the legality of CBD related products in the US. As far as the CBD related product contains less than or equal to 0.3 percent THC it is legal and safe to consume and manufacture in all of the states of The United States of America under federal law. 

Base Oil

Most articles go through details about CBD and CBD alone and skip the importance of the carrier oil. The product has more components than just cannabidiol. Well, we are going to explain to you how many types of base oils you will encounter while in the market purchasing CBD infused oils. 

The best choice according to experts is the MCT oils. The MCT oils are medium-chain triglycerides and the reason they are selected as the best option to carry CBD is because of their high absorption rate from the gastrointestinal system. 

Thus providing the highest bioavailability of CBD to the system. MCT oils can be extracted from different natural sources. Some commonly found MCT oils in the CBD industry are coconut oils and palm kernel oil. 

Coconut oil is valued more because of its additional benefits but palm kernel oil is not bad to work with as well. It is important to note that these oils impart very little flavor to the mix as the original flavor of CBD oil is strong and pungent enough. 

Other oils you might encounter include hemp seed oil or cannabis oil. Both of the oils are derived from different parts of the same plant. Both of them are useful in enhancing the viability of CBD oil just like broad-spectrum and full-spectrum CBD oils. 

Method of CBD Extraction

There are three main extraction processes used to extract CBD from the plant and infuse it into the oils. These methods even date back to the time when procurement, manufacturing, and usage were illegal in the US but the operations were running behind the curtain. 

The oldest method of extraction revolves around olive oil and the boiling of different parts of cannabis and hemp plants to infuse the oil with the plant’s benefits. By this method, all of the elements get equally infused in the oil. However, different spectrums of concentrations cannot be achieved. This is the reason that industries have let go of this dated method. 

The second method is the ethanol method. The working of the ethanol method is quite complex. However, we know for sure that during this method the chance of error is increased greatly. This may lead to the addition of unwanted elements in the mix. 

The third and last method of CBD extraction is the CO2 method. The machinery and process of extraction via this method are quite extensive and detailed which makes it a very expensive method. Extracting CBD using this method is the safest but it is also expensive. 

This is the main reason for the high cost of CBD oils in the market. However, you cannot possibly put a price on health and safety. Therefore, it is best to choose the CBD oil that has been extracted using the CO2 extraction method only. 


Just like we mentioned above that high potency oils cannot be tweaked our way to make customized CBD oils but luckily low potency oils can be customized. Many elements have been known to have amazing benefits in treating depression. 

If those elements can be added to the mixture of CBD oil then the benefits can be increased and it is always better to have an extra level of boost with therapeutic products. These beneficial elements include vitamin B1, B6, B12, choline, magnesium, and iron. 

If these vitamins and minerals are added to the CBD oil, you can easily substitute the CBD oil for other dietary supplements. 


Good quality CBD oils are not cheap at all, the prices of CBD oils reflect way more than what you have thought of. The price reflects the quality of the ingredients, the source of cannabis, the method of extraction, the concentration of CBD, and testing facilities used by the manufacturer. 

If you want to obtain the highest quality CBD Oil, you will have to pay a slightly higher price than cheap products that can be easily found in the market. We would advise you to spend a few extra bucks to ensure you get the highest quality CBD oil.

Frequently Asked Questions 

Q. Will CBD cure my depression once and for all?

A. CBD is a therapeutic element that has numerous benefits including safely restoring the chemical balance of the nervous system. The restoration of chemical balances is the number one solution to solving mental health problems including depression.

Using CBD to cure your depression is not a fast process. It requires an extensive amount of time to work its way through your system and fix what needs to be fixed. Hence, while CBD solves the problem of depression, you will have to be patient and let it work its charm on you. 

Q. How to choose the appropriate dose of CBD for depression

A. The correct method to choose a dose for your condition is to visit a medical professional. Depending upon the state of your disease the dose may vary as advanced problems require a higher dose. 

However, if you do not want to consult a medical practitioner, then start from a low potency CBD oil with a minimum dose of one ml per day. You can increase the dose after one week if no change is observed. Keep increasing the dose until your desired result is achieved. 

Final Word

This isn’t all you can know about depression and its treatment with CBD but surely this article contains enough information for you to have a clearer idea on how to choose the correct CBD oil. 

There is ample evidence available on the topic as most studies concerning CBD have turned in positive results. This indicates that the therapeutic effects of CBD are enough to treat depression. 

However, there are still variations in the disease state itself that might hinder the emergence of any beneficial effect. Buy the best CBD Oil for depression that we have mentioned above and you will feel better!

You have to wait with perseverance as CBD is not a synthetic drug that can produce an effect in a matter of minutes, it might take a few weeks to work its magic in your system but it will eventually come around and solve your sorrows.

Stay safe and healthy, folks!