Best Supplements to Help Depression

At this point, everyone is aware of mental illnesses and mental struggles that people go through. We, as a society, have moved so far and so forth and have realized the importance of mental health. With mental health awareness campaigns and months, the stigma around it is slowly but surely dying. 

According to survey research, approximately 16.2 million adults suffer from one or the other type of depression in the US alone. Unfortunately, depression is one of the most common mental disorders found among adults along with anxiety.

Supplements are the best help in this situation along with preventative drugs. Let’s take a look at the best supplements to help depression available in the market!

Our Overall #1 Rated Pick

Spruce Sleep ranger

  • Tested 
  • Enhances sleep 
  • High potency

Spruce is one of the well-known brands. It has a wide range of stress relief products. Spruce Sleep Ranger is an organic, pure, and natural product to prevent depression. The product is full of safe and wholesome ingredients. 

The capsules are easy to swallow as there is no unpleasant after taste and smell. You can consume capsules as per the prescription of a doctor. The supplement is a blend of effective minerals, nutrients, and vitamins.

Best Supplements to Help Depression – Products Comparison

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Best Supplements to Help Depression – Product Reviews

Top 10 Supplements to help depression out there

Spruce Sleep ranger

Spruce is one of the well-known brands. It has a wide range of stress relief products. Spruce Sleep Ranger is an organic, pure, and natural product to prevent depression. The product is full of safe and wholesome ingredients. 

The capsules are easy to swallow as there is no unpleasant after taste and smell. You can consume capsules as per the prescription of a doctor. The supplement is a blend of effective minerals, nutrients, and vitamins. 

The enzymes when mixed with other natural ingredients. It becomes more efficient. The supplement contains natural melatonin. It helps to restore and repair the cell membrane. The supplement is good for preventing tension, fatigue, and depression. 

The product is tested and checked thoroughly for the presence of toxins. It is free of metals, chemicals, and other pollutants. Melatonin in the supplement helps to boost energy in your brain and body.

The valerian root in the supplement is for peaceful sleep. If you have a regular sleep and wake cycle your brain feels fresh. It becomes easy to have a stress-free routine. The product is tested in the local lab during manufacturing.

It is also tested for artificial flavors, colors, and dyes. The ingredients are non-GMO, nut-free, and dairy-free. The supplement is cruelty-free as it is never tested on animals. Hemp and 5-HTTP in the supplement elevate the mood and promote relaxation.

Pros

  • Vegan 
  • Relieves anxiety 
  • Prevents depression
  • Enhances sleep 
  • Tasteless capsules
  • Tested 
  • Natural ingredients

Cons

  • None

Future Kind

Future Kind Super Vegan is a stress and anxiety-relieving supplement. It is completely organic, pure, and natural. The supplement is specially manufactured for anxiety and depression survivors of 2020. It has become famous over time.

The supplement is a very effective blend of three herbs; Ashwagandha, Lemon Balm, and Rhodiola. These herbs mixture supports the stress and anxiety. It helps to reduce tension and boost cognitive functions. 

The supplement aims to boost energy, elevates mood, and reduces depression. It is tested and checked clinically. The herbs added in the supplement are also researched clinically. The supplement has eco-friendly packaging as well. 

Ashwagandha is considered to be the king of Ayurveda herbs. It is studied thoroughly for its benefits. The herb is very beneficial for relieving stress and provides energy to you. Rhodiola is the second herb used in the supplement. 

It fights stress and fatigue. The herbs are also clinically tested to improve cognitive functions. Lemon Balm is also a naturally occurring herb that is very good for promoting calmness and relaxation in the body.

Pros

  • Vegan
  • Contains herbs 
  • Improves cognition 
  • Reduces stress 
  • Lowers depression

Cons

  • None

Mind Lab Pro

Mind Lab Pro is a natural, safe, and pure supplement for depression. It contains efficient ingredients that work to reduce stress and fatigue. Insomnia, tension, and anxiety can cause depression. It is better to start taking the supplements before the condition gets worse. 

The supplement contains a mix of bio-pathways and nootropics. It works for the benefit of the brain. The mixture boosts the brain’s immunity system and provides energy. It also helps to heal and restore brain cells. 

Nootropics are natural supplements that boost brain functions. It helps to reduce brain fog and prevent memory loss. The basic cognitive functions are also enhanced with the regular use of nootropics in your diet. It prevents age-relating brain health issues. 

The ingredients of the supplement are non-GMO, nut-free, and dairy-free. It is a complete plant-based supplement. The supplement is tested and checked in the local lab. It is also verified safe to consume by a third party.

The supplement is free of sugar, artificial flavors, colors, dyes, and preservatives. It is molecularly distilled to check the presence of any toxins like metals and chemicals. The supplement controls blood sugar levels and maintains heart health.

 

Pros

  • Vegan-friendly 
  • Prevents anxiety
  • Enhance cognition
  • Sugar-free
  • Boosts the energy 
  • Tested 
  • Relives depression

Cons

  • None

Performance Lab Stim

Performance Lab Stim is an effective supplement for depression. The supplement contains pure, efficient, and organic ingredients. Anxiety, stress, and fatigue can cause depression. The supplement is filled with clean and safe-to-consume ingredients. 

It helps to prevent and relieve tension. The supplement contains a mixture of healthy ingredients. It helps to repair and heal brain cells. It contains nutrients, minerals, and vitamins that protect the brain and boost its immunity.

The supplement contains non-GMO, nut-free, and dairy-free ingredients. It helps to normalize the sleep and wake routine. The blend of efficient ingredients prevents depression. It builds a protective shield in your brain which prevents any age-related mental issues.

The supplement elevates mood and energy levels. You will not feel drowsy and lazy all day. The safe and purity test reports are available on the website. It is also checked and verified safe to consume by an independent party.

Pros

  • Natural
  • Boosts immunity 
  • Enhances sleep
  • Lowers stress
  • Prevent memory loss 
  • Tested

Cons

  • None

Performance Lab Sleep

Performance Lab Sleep

Performance Lab Sleep is full of pure and natural ingredients. The supplement is manufactured for people facing anxiety and stress. Long-term anxiety can lead to deep-rooted depression. It is better to start taking essential nutrients. 

The supplement is tested and checked for the presence of toxins like harsh chemicals and metals. It is free of any pollutants. The ingredients include melatonin. It is effective for providing relief to the brain and body. 

The capsules are free of any smell and unpleasant flavors. You can consume them according to the prescription of the doctor. It contains a natural herb namely valerian root. It is an ancient herb used for preventing insomnia and stress.

The supplement elevated the mood and promotes a sense of calmness. It helps to regulate the sleep and wake routine. The supplement improves cognitive functions, memory, and prevents brain fog.

 

Pros

  • Vegan 
  • Enhances cognition
  • Prevents anxiety
  • Natural melatonin
  • Promotes calmness  
  • Tested

Cons

  • None

Cheef Botanicals CBD Capsules

Cheef Botanicals Vegan CBD Capsules are effective for relieving depression. Anxiety, stress, and fatigue can cause deep-rooted depression. It is better to start to take preventive supplements before it’s too late.

The supplement is clean and safe to consume. It is tested in the local lab and also by an independent party to make sure it is pure. The lab reports are available on the website for the public. The product is free of toxins, chemicals, and metals. 

It contains non-GMO, nut-free, and dairy-free ingredients. The supplement is hemp-rich. However, it is free of THC. The supplement is non-psychoactive and drug-free. It helps to repairs the immunity of the brain and boosts energy.

The capsules are high in strength and potency. It is also easy to consume as there is no unpleasant aftertaste and smell. The supplement is free of artificial colors, flavors, preservatives, and additives. It calms the body and brain which further reduces depression.

Pros

  • Vegan 
  • High potency 
  • Prevents anxiety
  • Tested
  • Prevents insomnia
  • Drug-free

Cons

  • None

Doctor’s Best

Doctor’s Best is a fast-acting supplement for stress. The supplement is packed with natural, pure, and clean ingredients. It contains high quality and sufficient vitamins for the body. The amount of magnesium in the supplement plays important role in preventing depression.

The magnesium reduces stress and tension. It promotes a sense of relaxation in the body. The supplement is good for relieving anxiety, fatigue, and insomnia. It is also an effective product for improving cognitive functions. 

The supplement is tested and checked for the presence of toxins. It is free of metals and chemicals. There are no artificial preservatives, flavors, and sweeteners present in the product. The supplement provides relaxation to the nerves. 

Long-term fatigue, tension, and stress can trigger depression. The supplement works fast in reaching brain receptors and relieves stress. It contains non-GMO, nut-free, and dairy-free ingredients. The mixings of the supplement are pure and legal. 

The supplement also helps to boost the immunity system. It builds a shield and prevents age-related mental issues. The supplement is good for memory loss, brain fog, and loss of focus. It is also gentle on your gut.

Pros

  • Plant-based 
  • Fast absorption
  • Prevents headaches 
  • Boosts  immunity 
  • Provides energy 
  • Reduces anxiety

Cons

  • Expensive

OLLY Goodbye Stress

OLLY Goodbye Stress is a well-known supplement. It is packed with vitamins, nutrients, and minerals for relieving stress. Anxiety and stress can cause deep-rooted depression. It is better to take care before it gets worse. 

The formula of the supplement is tested and checked for the presence of any impurities. It is free of metals, chemicals, and other toxins. The product is a unique blend of GABA and L-Theanine. These ingredients have several health benefits.

The supplement supports cognition and improves immunity. The gummies are a fun way to reduce and prevent depression. The gummies also contain a sufficient amount of lemon balm. It is a very famous relaxing ingredient.

GABA on the other hand is an essential nutrient for the brain. It improves memory and focus. The supplement gives you energy and you will not feel lazy. It is a drug-free and non-psychoactive supplement. 

The ingredients are non-GMO, nut-free, and dairy-free. It is a cruelty-free product and contains a mild natural flavor.

Pros

  • Natural 
  • Promotes relaxation
  • Improves immunity 
  • Tested 
  • Provides energy

Cons

  • None

NOW Supplements – True Focus

NOW supplements have become famous over time. True Focus is a stress and anxiety-relieving supplement. The supplement is designed and manufactured for treating depression and preventing deep-rooted stress. 

The supplement has several health benefits. It is full of minerals, nutrients, and vitamins. The mixtures of natural, pure, and clean ingredients help to boost immunity and energy. It also improves cognitive functions. 

The ingredients are non-GMO, nut-free, and dairy-free. It is tested and checked for the presence of any impurities. The supplement is free of chemicals, metals, and other toxins. There are no artificial flavors, dyes, and preservatives present in the supplement. 

The product is also cruelty-free as it is not tested on animals. The ingredients of the supplement promote relaxation and calmness throughout the body. It helps to repair and improves brain cells. 

Moreover, the supplement is GMP-rated and sodium-free. It helps to improve focus, concentration, and sleep routine.

 

Pros

  • Plant-based 
  • Improve sleep 
  • Prevents anxiety
  • Tested 
  • Elevates mood

Cons

  • Expensive

Gaia Herbs- Emotional Balance

Gaia Herb’s emotional balance is formulated with all of the natural ingredients. It contains oats, rosemary, passionflower, Gotu kola, ginkgo, and other herbs. The ingredients hen combined helps to improve the central nervous system.

It also promotes a sense of calmness and relaxation in the body. The supplement supports a good mood. The herbs in the supplement are organically grown on the company’s farms. It is completely plant-based and there are no artificial mixings present.

The ingredients are free of stabilizers, fillers, binders, and solvents. It is manufactured under strict supervision on the Gaia farm in the USA. The herbs are all-natural that boost immunity and provides energy. 

The supplement is based on a unique dual-extraction technology that delivers the high potency and pure extract of herbs. The ingredients are non-GMO, nut-free, soy-free, and dairy-free.

 

Pros

  • Vegan 
  • Relieves anxiety 
  • Prevents depression
  • Enhances sleep 
  • Tasteless capsules
  • Tested 
  • Natural ingredients

Cons

  • None

Best Supplements to Help Depression – Buying Guide

Antidepressants are a necessary medication for anyone suffering from depression. Along with the medications, other amendments are needed to ensure proper recovery and quality of life, just like any other disease. 

Along with improved routine, proper diet, health supplements are another positive addition to the routine. These supplements need to meet certain demands and certain factors met to be considered as a perfect supplement for depression patients. 

Depression will have certain added chemicals and nutrients that will help the brain get back up and healthy again. So, let’s look at these factors,

Omega 3

I know, I know. You are absolutely tired of hearing about Omega 3 and all the advantages of fish oils. but all these advantages are real and authentic. Omega 3 has made its name the best possible natural supplement and rightfully so. 

Omega 3 are essential fatty acids. The intake of these supplements in the everyday diet can cure depression by both reducing inflammations and interacting with mood-inducing molecules. Some research has shown that omega 3 has plausible health and healing benefits when it comes to depression. 

There are tons of articles online with solid sources that claim that omega 3 does have positive effects on depressive patients. A study conducted in 2020 showed the healing effects of omega 3 on postpartum depression.

Vitamin D

“Get out more.” This may be the last thing you want to hear but it is necessary. Do step outside in the sun. Not only does it actually help with your mood, but it also helps with the production of vitamin D in the body. 

Several investigative types of research have shown that vitamin D and depression have reciprocated relationships. People suffering from depression are seen to have lower levels of vitamin D. Now, how is vitamin D help depression, well, it can help by more than one pathway, mood regulation, inflammation reduction, and protection against neurocognitive dysfunction. 

Research work conducted in 2020 showed the effects of vitamin D IU drips on patients showing symptoms of depression. A noticeable decline in the depression levels was seen after the introduction of vitamin D.

Folic Acid

You may have heard of folate; well folic acid is the synthetic form of that vitamin B. Folate is commonly found in green vegetables, which is why eat your greens. Folate deficiency, along with vitamin D deficiency is quite common among people with depression. 

Folate or folic acid helps the body in maintaining proper brain health by helping the brain produce more and more neurotransmitters which help the brain build a better relationship with the body. Improved levels of folate have been seen to wildly improve depression symptoms. 

Although some research has shown the effects of folic acid on depression, there is also a few research that shows that folic acid on its own is unable to do so. There have also been some reported reports that suggest that male and female doses be different to see noticeable results. 

Rhodiola

Rhodiola is the most common herb found in most health supplements. This is due to the wide variety of benefits that Rhodiola provides. One of the many benefits of this herb is its antidepressant properties. This is because this herb can improve nerve communication with the cell and soothe the hypothalamic-pituitary-adrenocortical axis or HPA axis. 

This allows the brain to stop overactivity that’ll allow you to sleep better and reduce stress responses which in turn reduces the depression and anxiety symptoms. A study conducted in 2015 showed that the use of 340 mg of Rhodiola allowed the symptoms of depression to subside a considerable level. 

Zinc

Zinc is one of the few minerals that are wildly important for the health and the integrity of neurotransmitters and also helps in the regulation of the overall communication pathway. Other than that, this handy mineral has antioxidant and anti-inflammatory properties. 

As mentioned above, along with folate and vitamin D, zinc deficiency is also seen to be directly involved with depression. This claim was soon proven via scientific property. A study conducted in 2013, studied the blood zinc levels drop and highs among both healthy and depressed patients. 

The people suffering from depression had fewer amounts of zinc in the blood, 1.2 µg/mL to be exact. 

S-Adenosylmethionine

S-Adenosylmethionine or sAME is a body-made substance that helps boost up the production of serotonin, norepinephrine, and dopamine neurotransmitters. The levels of all of these chemicals are seen to be lower than found on a healthy individual. 

This means that the chemicals are imbalanced which needs to be brought back to a reasonable balance, which sAME can do. sAME has quite a few backup research work that shows the power of this substance in chemical balancing. 

Out of a total of 8 research work done, 6 have supported that sAME is far more effective in treating depressive symptoms than any placebo. Research has also shown that sAME mixed with tricyclic antidepressants work quite a bit faster than regular antidepressants. 

Magnesium 

Magnesium is another one of the most important minerals. Magnesium deficiency is usually one of the most commonly detected links that either leads to depression or are common effects of depression. Either way, magnesium is involved with depression and is very much an important health nutrient. 

A survey study showed that 126 volunteering participants each suffering from some level of depression. All participants were given 248 mg of magnesium every day for around 6 weeks. Each individual showed improvements in the level of depression compared to different placebos. 

Creatine

Creatine is a commonly found organic compound found in our body. creatine performs quite a lot of functions but most importantly, creatine helps the body in the proper conservation of brain energy. Along with altered chemical balance, the altered brain energy is seen to affect the depression inset and related symptoms. 

Although this is supported in theory, there is still a lot of research that is still needed to be able to fully support this claim. A study has shown that 2 to 10 mg of creatine every day led to a vast improvement in the symptoms of major depressive disorder. 

St. John’s Wort

These supplements are an extract of a herbal plant known as Hypericum perforatum. How St. John’s wort can help the body is by helping the brain reduce the amounts of cortisol. Cortisol molecules are stress-associated and aid the brain in the production of hay molecules such as serotonin, dopamine, and norepinephrine. 

Several of research work has supported St. John’s wort. There is a lot of work done to compare St. John’s wort with the more conventional tricyclic antidepressant medications. Although results were affirmative, there is still a need for more thorough research work.

Turmeric 

Turmeric has been used in both Chinese and Indian medications for centuries now. Both cultures have been making the best of the turmeric by using the said spice in ancient medicine. Modern sciences have given us a deep insight as to how turmeric actually affects our brain.

According to the research, curcumin is extracted from turmeric, which the real star of the show here. Turmeric owes all its healing and medicinal properties to curcumin. Curcumin can find and reduce the roaming free radicals that allow the brain to have less inflammation. 

Studies conducted in 2016 were able to conclude the direct relationship between inflammation in the brain and depression. It is, however, unclear who causes who. 

Amino Acid

Amino acid is a building block, plain and simple. The amino acids are building blocks of both proteins and neurotransmitters. We know that neurotransmitters are very much necessary to provide the proper communication path between the body and the brain. 

Proper communication can reassure a healthy brain which can easily combat the stress molecules and hence, keep depression at bay. 

Vitamin C

Yes, vitamin C deficiency is linked with depression. Several adverse psychiatric effects have been seen due to a lack of vitamin C in the body. vitamin C is a recurring nutrient that will pop up in almost all supplements. 

This is because vitamin C deficiency is quite common but not up to dangerous levels. This will, of course, result in some type of serious outcome such as scurvy. Recent studies have shown that along with curvy, vitamin C deficiency will bring about several cognitive impairments such as depression and anxiety. 

Melatonin

If you have had to, at some point, deal with sleeplessness or restlessness, you know what melatonin is. Melatonin is a hormone that regulates both the sleep cycle and the circadian rhythm. Sleep is a very important part of our routine. 

We see that lack of sleep can be detrimental to not only bodily health but also to the mind. Lack of proper and healthy amount of sleep will lead to more pent-up stress and will eventually lead to some type of depression. 

A 2017 and 2018 independent researchers concluded the same result, that a healthy amount of melatonin will help reduce the effects and symptoms of depression.  

Best Supplements to Help Depression – FAQs

1. Is it safe to take supplements with antidepressants?

Most supplements are safe to be taken with prescribed antidepressants. But, we’d advise you to not take both as there may be some clashing ingredients depending upon the treatment. It is best to ask your doctor if a certain supplement is okay to be taken with meds. 

2. Will supplements work for SAD?

Absolutely. In this case, lack of vitamin D is usually the leading cause. The addition of vitamin D and other nutrients that you may be lacking will help you instantly feel better. 

3. Do supplements really help?

Supplements are just nutrients that you could be lacking. We’ve seen that lack of nutrients can lead to many health concerns. Supplements will help you stay healthy.

Best Supplements to Help Depression – Conclusion

Depression is, no doubt, quite a pain to deal with. It comes up randomly, drains you of all energy and motivation, and even leaves you feeling alone and unwanted. It is a serious disorder and should be treated so. 

The first thing to know is to realize that you are not alone. There are so many hotlines, online communities, and medical help available for you. You can always ask for help and create your own safe space. 

There is nothing wrong with having depression, neither is there anything wrong with asking for help. As soon as a doctor gives you a diagnosis, you can start your medications which will help you feel a lot better. 

You need your newfound energy to turn your life back around one step at a time. Best supplements to help depression are one of those steps. Here’s to a healthier and happier you!